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ნინა კულიკოვა

პოზიცია: პროფესორი

ელფოსტა: n.kulikova@agruni.edu.ge

 

განათლება

2003 საკანდიდატო დისერტაცია იმუნოლოგიაში, თბილისის სახელმწიფო უნივერსიტეტი
2000 მაგისტრატურა იმუნოლოგიის სპეციალობით, თბილისის სახელმწიფო უნივერსიტეტი
1998 ბაკალავრიატი, ბიოლოგიის სპეციალობა (წარჩინებით), თბილისის სახელმწიფო უნივერსიტეტი 

 

პუბლიკაციების ჩამონათვალი

რჩეული პუბლიკაციები

  1. Kulikova N., Lydyard P.M., Vispute K., Steele A., Tsertsvadze T., Botschorishvili E., Mitskevich N., Nathwani N., Clark E.A., Porakishvili. N. Effect of CD180 ligation or CD180/IgM sequential ligation on signalling pathways in “Responder” CLL cells. EAACI Congress, Geneva, Swirzerland, 2012 (abstract)
  2. Porakishvili N., Lydyard P.M., Vispute K., Memon A., Steele A., Kulikova N., Nathwani A., Rai K.R., Damle R.N., Clark E.A., Chiorazzi N. Pro-survival signalling in “Responder” CLL cells following ligation of CD180. Clin Lymph Myel Leuk, 2011, 11 (Suppl 2): S164-S165 (abstract)
  3. Kulikova N., Botchorishvili E., Tsertsvadze T., Tsagareishvili P., Sereda L., Tevzadze M., Ghirdaladze M., Gachechiladze N., Mitskevichi N., Lydyard P., Porakishvili N. CD180 surface expression by B-chronic lymphocytic leukemia (B-CLL) cells correlates with the percentages of smudge cells in B-CLL blood smears. The 4th International IMBG Conference for young scientists, 2011 (abstract)
  4. Porakishvili N., Memon A., Vispute K., Kulikova N., Clark E., Rai K., Natwani A., Damle R., Chiorazzi N. and Lydyard P. CD180 functions in activation, survival and cycling of B chronic lymphocytic leukaemia cells. Br J Haematol. , 2011, 153(4):486-98. Asatiani N., Abuladze M., Kartvelishvili T., Kulikova N., Asanishvili L., Holman H.-Y., Sapojnikova N. Response of antioxidant defense system to chromium (VI)-induced cytotoxicity in human diploid cells. Biometals, 2010, 23:161-172
  5. Porakishvili N., Lydyard P., Bremser A., Vispute K., Memon A., Kulikova N., Clarke E., Rai K.R., Nathwani A., Damle R.N., Chiorazzi N. B-cell lymphocytic leukemia (B-CLL) cells unresponsive to CD180 ligation fail to respond to anti-IgM stimulation as well. Leukemia&Lymphoma, 2010, 3582 (abstract)
  6. Porakishvili N., Memon A., Atik C., Clark E.A., Kulikova N., Nathwani A., Kaufman M.S., Rai K.R., Damle R.N., Chiorazzi N., Lydyard P.M. Ligation of CD180 is a strong activation, proliferation and survival signal for B cells from normal subjects and certain B-CLL patients. Haematologica,2009, 94(s3), s37 (abst.4.31) ( XIII iwCLL 2009, Barcelona, Spain (abstract))
  7. Kulikova N., Tsertsvadze T., Tsagareishvili P.,Sereda L., Tevzadze M., Kardava L., Gachechiladze N., Lukhumaidze M., Ghirdaladze M., Amaglobeli N., Porakishvili N. Association between seropositivity for cytomegalovirus (CMV) and CD4+ Cytotoxic T cells expansions in patients with B-cell chronic lymphocyte leukaemia (B-CLL) and healthy controls. Proceedings of the Georgian Academy of Sciences, 2009, Vol. 7, No. 3-4, 41-46
  8. Abuladze M, Asatiani N, Kartvelishvili T, Kuikova N, Sapojnikova N. The comparison of chromium mediated cell responses in two different human cell lines. Metal Ions in Biology and Medicine,2008, p.281-287
  9. Porakishvili N., Memon A., Kulikova N., Manoussaka M., Lydyard P.M.The role of TLRs in adaptive immune responses. EuroSciCon (Toll-like receptors - Investigating innate immunity & infection) 25th Sept 2007 (http://www.euroscicon.com/archivehighlights.html) (abstract)
  10. Memon A, Lydyard PM, Kulikova N, Nathwani A, Clark EA and Porakishvili N. Impaired activation of B-CLL cells through CD180-ligation is associated with a significantly decreased responsiveness via CD40, IgM and IL-4. XII iwCLL 2007, London, UK (abstract)
  11. Kulikova N, Okujava R, Kardava L, Kartvelishvili M, Iosava G, Ghirdaladze D, Porakishvili N. Apoptosis induction in B-chronic lymphocytic leukaemia cells in vitro via ligation of CD19. Proc Geo Acad Sci. 2006, 32, 2:331-339
  12. Kulikova N, Okujava R, Janikashvili N, Gabunia Kh, Mitskevichi N, Tsertsvadze T, Tsagareishvili P, Ghirdaladze D, Porakishvili N. Toll-like receptors expression profile in patients with B cell Chronic Lymphocytic Leukaemia (B-CLL). Proc Geo Scad Sci, 2006, 32, 3:523-530
  13. Jordania Ts. , Kulikova N. , Okujava R. , Shelegia K. , Sereda L. , Tevzadze M. , Ghirdaladze M. , Porakishvili N. Detection of cell cycle phase distribution in B-chronic lymphocytic leukaemia (B-CLL) cells after in vitro ligation with anti-CD5 or anti-CD19 monoclonal antibodies. Proc Geo Scad Sci, 2006, 32, 3: 597-603
  14. Porakishvili N, Kulikova N, Jewell AP, Yoinou PY, Nedelec S, Yong K, Nathwani A, Heelan B, Duke V, Hamblin TJ, Wallace P, Ely P, Clark EA and Lydyard PM. Differentiational expression of CD180 by B chronic lymphocytic leukaemic cells with mutated and unmutated Ig Vh genes. Br J Haematol. , 2005, 131, p. 313-319
  15. Porakishvili N., Kulikova N., Manoussaka M, Jewell A.P.,Youinou P.Y., Nedelec S., Yong K., Nathwani A., Heelan B., Duke V., Hamblin T.J., Wallace P., Ely P., Clark E.A., Lydyard P.M. Differential expression of CD180 and sIgM by B chronic lymphocytic leukaemia cells (B-CLL) using mutated and unmutated Vh genes. Blood, 2004, Vol.104, No.11, 768a (abstract)
  16. Porakishvili N., Manoussaka M., Kulikova N., Walton A.J., Nathwani A., Stevenson F., Clark E.A., Lydyard P.M. Activation and proliferation of B cell chronic lymphocytic leukaemic (B-CLL) cells through anti-CD180, anti-CD40 and IL-4. Blood, 2004,Vol.104, No.11, 277b (abstract)
  17. Asatiani N., Sapojnikova N., Abuladze M., Kartvelishvili T., Kulikova N., Kiziria E., Namchevadze E., Holman H.-Y. Effects of Cr(VI) long-term and low-dose action on mammalian antioxidant enzymes (an in vitro study). Journal of Inorganic Biochemistry, 2004, 98, 490-496
  18. Akhobadze T., Jordania Ts., Kulikova N., Kardava L., Gachechiladze N. , Ghirdaladze D., Iosava G., Porakishvili N. Patterns of the expression of CD32 and CD64 on monocytes of patients with B cell chronic lymphocytic leukemia. Proceedings of the Georgian Academy of Sciences, Biol. Ser. B, 2004 Vol.2, No.3-4 , 39-41
  19. Porakishvili N, Kulikova N , Jewell AP, Younou PY, Yong K, Nathwani A, Heelan B, Duke V, Stevenson FK, Hamblin TJ, Wallace P, Ely P, Clark EA, Lydyard PM. Preferential expression of CD180 by B cell chronic lymphocytic leukemia (B-CLL) cells using IgVh mutated than those using IgVh unmutated genes. Leukemia&Lymphoma, 2003, 153(abstract)
  20. Akhobadze T., Kapanadze T., Baloyan D., Kulikova N., Kardava L., Kartvelishvili M., Jordania Ts., Gabunia Kh., Porakishvili N. Abberant expression of Fc γ-receptor (CD64) by monocytes and neutrophils from patients with B cell chronic lymphocytic leukemia. Proceedings of the Georgian Academy of Sciences, Biol. Ser. B, 2003 Vol.1, No.1-2 , 39-41
  21. Porakishvili N., Kulikova N., Sundar S., Jewell A.P., Youinou P.Y. , Nedelec S., Yong K., Stevenson F., Hamblin T.J., Wallace P., Ely P., Clark E.A., Lydyard P.M. Heterogeneity of expression of Toll-like receptor RP105 (CD180) by B cell chronic lymphocyticleukaemic (B-CLL) cells. Blood, 2002, suppl 52. (abstract)
  22. Gabunia Kh., Kardava L., Kulikova N., Jordania Ts., Burjanadze L., Sereda L., Porakishvili N. Phagocytosis and the regulation of apoptosis in B-chronic lymphocytic leukaemia. Bulletin of the Georgian Academy of Sciences, 2002, 166: 1.
  23. Porakishvili N , Mageed R, Jamin C, Pers J-O, Kulikova N, Renaudineau Y, Lydyard PM, Youinou PY. Recent progress in the understanding of B cell functions in autoimmunity. Scand J Immunol., 2001, 54: 30-38.
  24. Kardava L., Kulikova N., Tevzadze M., Gabunia Kh ., Barbakadze V., Ghirdaladze D., Iosava G., Porakishvili N. The cell cycle progression of B-chronic lymphocytic leukaemia cells in vitro. Proceedings of the Georgian Academy of Sciences, 2001, 27:4-6.
  25. Kulikova N. , Lydyard P.M., Porakishvili N. Induction of apoptosis by anti-CD5 monoclonal antibodies in B-CLL cells correlates with the level of CD79b expression. Proceedings of the Georgian Academy of Sciences, 2001, 27: 363-368.
  26. Porakishvili N., Kulikova N., Kalber T., Jewell A., Patterson K., Yong K., Youinou P.Y., .Lydyard P.M. Spontaneous apoptosis of tumour cells in patients with B chronic lymphocytic leukaemia (B-CLL) is inhibited by CD40 ligation. Immunology, 2000, 101, suppl 1, 26. abstract)
  27. Porakishvili N, Kulikova N , Elliott S, Jewell AP, Patterson K, Yong K, Pers J-O, Youinou P, Lydyard PM. Apoptosis of leukaemic cells in patients with B chronic Lymphocytic Leukaemia (B-CLL) induced by the ligation of CD5. Blood, 1999, 94: 10, Suppl. 1, 313b. abstract)
  28. Porakishvili N, Kulikova N. Correlation of the expression of some cell surface molecules on tumour cells of patients with B Chronic lymphocytic leukaemia (B-CLL). Int J Immunorehab, 1999, 14, 73.(abstract) 
კახა ბენდუქიძის კამპუსი, დავით აღმაშენებლის ხეივანი 240